Rationale

Information on COVID-19 is changing by the day, even by the hour. The quest for new knowledge has grown exponentially. This has made the information on COVID-19 essentially overwhelming. In recognition of this challenge, the knowledge management unit of the Centre for Innovative Drug Development & Therapeutic Trials for Africa (CDT-Africa) determined that curating this knowledge in a reliable and timely way was essential to ensure that the changing knowledge is usable and informs medical discovery and development. This page is the result of that determination. The synthesised daily update is based on publications from peer reviewed journals, preprints and publications by global, national and regional bodies.

Initial synthesis of the epidemiology, pathogenesis, diagnosis, treatment and approaches to control

Information on COVID-19 is changing by the day, even by the hour, and the quest for new knowledge has grown exponentially. Within just the past three months, over 500 clinical trials have been proposed and over 150 diagnostic tests have been developed. This has made the information on COVID-19 essentially overwhelming. In recognition of this challenge, the knowledge management unit of the Centre for Innovative Drug Development & Therapeutic Trials for Africa (CDT-Africa) determined that curating this knowledge in a reliable and timely way was essential to ensure that the changing knowledge is usable and informs medical discovery and development. The main objective of this initial document is to provide clinical and public health practitioners as well as researchers and the public a synthesis of the what is known about the epidemiology, pathophysiology, public health and holistic care approaches to COVID 19. The primary targets are readers in Ethiopia and the region. We have curated the information from standard guidelines and reputable journals and sources we believed were reliable. Although original sources are cited, we have used the sources freely as we saw fit. We have also included at the end of this document links to additional resources that we thought would be helpful to readers. We plan to update the information regularly (at least daily) in light of the emerging evidence. Please note that, this document does not attempt to provide treatment guidelines. The relevant national and international guidelines have to be consulted for that. However, we hope that this document and the subsequent updates will serve as a resource in bringing this epidemic under control in Ethiopia and Africa.